Lompoc Valley Medical Center, formerly known as Lompoc Healthcare District, was the first operating Healthcare District hospital established in California and was created in 1946 by the Santa Barbara County Board of Supervisors. The 463-square-mile district includes the city of Lompoc, Mission Hills, Mesa Oaks, Vandenberg Village, a portion of Vandenberg Air Force Base and the area east toward Buellton.

Lompoc Valley Medical Center provides quality inpatient, outpatient, and long-term healthcare. The District offers a variety of inpatient and outpatient services including: physical therapy, hematology/oncology, diagnostic imaging, laboratory services, sleep studies, and primary and specialty care physicians.